Justification of the role of rehabilitation assistance in lymphedema of the upper extremities based on foreign experience (a literature review)

Authors

  • Solomiia Kopytko Department of Therapy and Rehabilitation, Lviv State University of Physical Culture named after Ivan Boberskyj, Lviv State Regional oncology treatment and diagnostic Center, Ukraine https://orcid.org/0000-0002-9967-1183
  • Olha Bas Department of Therapy and Rehabilitation, Lviv State University of Physical Culture named after Ivan Boberskyj, Lviv State Regional oncology treatment and diagnostic Center, Ukraine https://orcid.org/0000-0003-2328-3093
  • Andriy Hrynkiv Department of Therapy and Rehabilitation, Lviv State University of Physical Culture named after Ivan Boberskyj, Lviv State Regional oncology treatment and diagnostic Center, Ukraine https://orcid.org/0009-0006-9216-9998
  • Andriy Vovkanych Department of Therapy and Rehabilitation, Lviv State University of Physical Culture named after Ivan Boberskyj, Ukraine https://orcid.org/0000-0002-1628-4699
  • Myroslava Hrynkiv Department of Anatomy and Physiology, Lviv State University of Physical Culture named after Ivan Boberskyj, Ukraine https://orcid.org/0000-0001-8727-110X

DOI:

https://doi.org/10.15391/prrht.2025-10(1).04

Keywords:

lymphedema, physical exercises, manual lymphatic drainage, bandaging

Abstract

Purpose. Lymphedema is a chronic condition of the lymphatic system that results from impaired lymphatic drainage. In adult practice, secondary lymphedema, which arises as a consequence of the treatment of oncological diseases, notably breast cancer, is predominant. One of the most common types is upper limb lymphedema. This condition is characterized by swelling, a sensation of heaviness in the limb, pain, and limited range of motion. According to various statistics, regardless of the chosen treatment methods, edema develops in 10% to 80% of breast cancer patients. The issue of timely rehabilitation for patients with lymphatic edema of the extremities remains relevant due to the widespread prevalence of this condition and its severe complications.

Material & Methods. General scientific: analysis, synthesis, generalization. The search was conducted in electronic databases PubMed/MedLine, PEDRo, International Clinical Trials Registry Platform, Cochrane Library.

Results. The rehabilitation program for lymphedema was developed quite a long time ago, and today there are many rehabilitation methods. However, discussions about the main components of oncological rehabilitation are still ongoing. Clinical studies from different countries of the world were included in the review. A total of 10 completed studies and one ongoing study were analyzed. The most points on the PEDRo scale were obtained by studies related to physical exercises and various elements of complex therapy. Two studies scored an overall score of 8 out of 10, five studies scored 7 out of 10, and the other studies scored 6, 5, and 4, respectively.

Conclusions. In recent years, the number of studies on the topic of lymphedema is increasing. New and established rehabilitation methods are being tested in research. There is a tendency to use only proven and effective means and methods of rehabilitation.

 

References

Ali, K.M., Gammal, E.R.El, & Eladl, H.M. (2021). Effect of Aqua Therapy Exercises on Postmastectomy Lymphedema: A Prospective Randomized Controlled Trial. Annals of Rehabilitation Medicine, 45(2), 131. https://doi.org/10.5535/ARM.20127

Anderson, E.A., Anbari, A.B., Armer, N.C., & Armer, J.M. (2019). Lymphoedema therapists: a national and international survey. Journal of lymphoedema, 14(1), 22–24. https://bit.ly/4i22zNR

Bahtiyarca, Z.T., Can, A., Ekşioğlu, E., & Çakcı, A. (2018). The addition of self-lymphatic drainage to compression therapy instead of manual lymphatic drainage in the first phase of complex decongestive therapy for treatment of breast cancer-related lymphedema: A randomized-controlled, prospective study. Turkish journal of physical medicine and rehabilitation, 65(4), 309–317. https://doi.org/10.5606/tftrd.2019.3126

Damstra, R.J. (2011). Upper Limb Lymphedema. In: Lee, BB., Bergan, J., Rockson, S. (eds) Lymphedema. Springer, London. https://doi.org/10.1007/978-0-85729-567-5_35

de Sire, A., Losco, L., Lippi, L., Spadoni, D., Kaciulyte, J., Sert, G., Ciamarra, P., Marcasciano, M., Cuomo, R., Bolletta, A., Invernizzi, M., & Cigna, E. (2022). Surgical Treatment and Rehabilitation Strategies for Upper and Lower Extremity Lymphedema: A Comprehensive Review. Medicina, 58(7), 954. https://doi.org/10.3390/medicina58070954

Deacon, R., de Noronha, M., Shanley, L., & Young, K. (2019). Does the speed of aquatic therapy exercise alter arm volume in women with breast cancer related lymphoedema? A cross-over randomized controlled trial. Brazilian Journal of Physical Therapy, 23(2), 140. https://doi.org/10.1016/J.BJPT.2018.11.004

Document, C., (2020). The diagnosis and treatment of peripheral lymphedema: 2020 consensus document of the international society of lymphology, Lymphology, 53(1), 3-19. https://doi.org/10.2458/lymph.4649

Forner-Cordero, I., Muñoz-Langa, J., DeMiguel-Jimeno, J. M., & Rel-Monzó, P. (2021). Physical therapies in the decongestive treatment of lymphedema: A randomized, non-inferiority controlled study. Clinical Rehabilitation, 35(12), 1743–1756. https://doi.org/10.1177/02692155211032651

Greene, A. K., & Goss, J. A. (2018). Lymphedema Management: Diagnosis and Staging of Lymphedema. Seminars in Plastic Surgery, 32(1), 12–16. https://doi.org/10.1055/S-0038-1635117

Guyatt, G. H., Sackett, D. L., & Cook, D. J. (1993). Users’ guides to the medical literature. II. How to use an article about therapy or prevention. A. Are the results of the study valid? Evidence-Based Medicine Working Group. JAMA, 270(21), 2598–2601. https://doi.org/10.1001/jama.270.21.2598

Kilbreath, S.L., Ward, L.C., Davis, G.M., Degnim, A.C., Hackett, D.A., Skinner, T.L., & Black, D. (2020). Reduction of breast lymphoedema secondary to breast cancer: a randomised controlled exercise trial. Breast cancer research and treatment, 184(2), 459–467. https://doi.org/10.1007/s10549-020-05863-4

Lawenda, B. D., Mondry, T. E., & Johnstone, P. A. S. (2009). Lymphedema: A primer on the identification and management of a chronic condition in oncologic treatment. CA: A Cancer Journal for Clinicians, 59(1), 8–24. https://doi.org/10.3322/CAAC.20001

Lee, B.B. (2008). Lymphatic Malformation. In: Lymphedema. Springer, London. https://doi.org/10.1007/978-1-84628-793-0_4

Lee, Byung-Boong & Bergan, John & Rockson, Stanley. (2011). Lymphedema: A Concise Compendium of Theory and Practice. https://doi.org/10.1007/978-0-85729-567-5

Ligabue, M.B., Campanini, I., Veroni, P., Cepelli, A., Lusuardi, M., & Merlo, A. (2019). Efficacy of self-administered complex decongestive therapy on breast cancer-related lymphedema: a single-blind randomized controlled trial. Breast cancer research and treatment, 175(1), 191–201. https://doi.org/10.1007/s10549-019-05136-9

Mercier, G., Pastor, J., Moffatt, C., Franks, P., & Quéré, I. (2019). LIMPRINT: Health-Related Quality of Life in Adult Patients with Chronic Edema. Lymphatic Research and Biology, 17(2), 163. https://doi.org/10.1089/LRB.2018.0084

Morgan, C.L. (2008). Medical Management of Lymphedema. In: Lymphedema. Springer, London. https://doi.org/10.1007/978-1-84628-793-0_5

Muñoz-Alcaraz, M. N., Pérula-de-Torres, L. Á., Serrano-Merino, J., Jiménez-Vílchez, A. J., Olmo-Carmona, M. V., Muñoz-García, M. T., Bartolomé-Moreno, C., Oliván-Blázquez, B., & Magallón-Botaya, R. (2020). Efficacy and efficiency of a new therapeutic approach based on activity-oriented proprioceptive antiedema therapy (TAPA) for edema reduction and improved occupational performance in the rehabilitation of breast cancer-related arm lymphedema in women: a controlled, randomized clinical trial. BMC cancer, 20(1), 1074. https://doi.org/10.1186/s12885-020-07558-x

Norton S. & Zuther J. E. (2012). Lymphedema Management: The Comprehensive Guide for Practitioners. Thieme Medical Publishers.

Omar, M. T. A., Gwada, R. F. M., Omar, G. S. M., El-Sabagh, R. M., & Mersal, A. A. E. (2020). Low-Intensity Resistance Training and Compression Garment in the Management of Breast Cancer-Related Lymphedema: Single-Blinded Randomized Controlled Trial. Journal of cancer education : the official journal of the American Association for Cancer Education, 35(6), 1101–1110. https://doi.org/10.1007/s13187-019-01564-9

Pasyar, N., Barshan Tashnizi, N., Mansouri, P., & Tahmasebi, S. (2019). Effect of yoga exercise on the quality of life and upper extremity volume among women with breast cancer related lymphedema: A pilot study. European journal of oncology nursing: the official journal of European Oncology Nursing Society, 42, 103–109. https://doi.org/10.1016/j.ejon.2019.08.008

Patel, K. M., Lin, C. Y., & Cheng, M. H. (2015). A Prospective Evaluation of Lymphedema-Specific Quality-of-Life Outcomes Following Vascularized Lymph Node Transfer. Annals of surgical oncology, 22(7), 2424–2430. https://doi.org/10.1245/s10434-014-4276-3

Sen, E. I., Arman, S., Zure, M., Yavuz, H., Sindel, D., & Oral, A. (2021). Manual Lymphatic Drainage May Not Have an Additional Effect on the Intensive Phase of Breast Cancer-Related Lymphedema: A Randomized Controlled Trial. Lymphatic research and biology, 19(2), 141–150. https://doi.org/10.1089/lrb.2020.0049

Smykla, A., Walewicz, K., Trybulski, R., Halski, T., Kucharzewski, M., Kucio, C., Mikusek, W., Klakla, K., & Taradaj, J. (2013). Effect of Kinesiology Taping on breast cancer-related lymphedema: a randomized single-blind controlled pilot study. BioMed research international, 2013, 767106. https://doi.org/10.1155/2013/767106

Tantawy, S. A., Abdelbasset, W. K., Nambi, G., & Kamel, D. M. (2019). Comparative Study Between the Effects of Kinesio Taping and Pressure Garment on Secondary Upper Extremity Lymphedema and Quality of Life Following Mastectomy: A Randomized Controlled Trial. Integrative cancer therapies, 18, 1534735419847276. https://doi.org/10.1177/1534735419847276

Thiadens, S. R. J., Stewart, P. J., & Stout, N. L. (2010). 100 questions & answers about lymphedema.

Torres-Lacomba, M., Navarro-Brazález, B., Prieto-Gómez, V., Ferrandez, J. C., Bouchet, J. Y., & Romay-Barrero, H. (2020). Effectiveness of four types of bandages and kinesio-tape for treating breast-cancer-related lymphoedema: a randomized, single-blind, clinical trial. Clinical Rehabilitation, 34(9), 1230–1241. https://doi.org/10.1177/0269215520935943

World Health Organization (Ed.) (2019). ICD-10 Version:2019. https://icd.who.int/browse10/2019/en

Downloads

Published

2025-02-28

How to Cite

Kopytko, S., Bas, O., Hrynkiv, A., Vovkanych, A., & Hrynkiv, M. (2025). Justification of the role of rehabilitation assistance in lymphedema of the upper extremities based on foreign experience (a literature review). Physical Rehabilitation and Recreational Health Technologies, 10(1), 27–34. https://doi.org/10.15391/prrht.2025-10(1).04

Issue

Section

Original Scientific Article